冠状病毒病2019年术后妄想的相关风险因素:观察性队列研究的二次分析
Yi-Heng Liu1, Chenghong Hu2, Xia-Min Yang1
1Department of Anesthesiology, Huashan Hospital of Fudan University, Shanghai, China.
在手术前7周内最近出现COVID-19 (冠状病毒病2019) 症状,增加了术后妄想 (POD) 的风险. 这种风险在65岁以下的患者中尤为明显.
科学领域:
- 麻醉学和外科手术期间的医学.
- 传染性疾病 传染性疾病
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 2019年手术前冠状病毒病 (COVID-19) 对术后神经系统结果的影响尚不清楚.
- 手术后妄 (POD) 是手术后的一个常见并发症.
- 调查COVID-19相关的风险因素,如手术后感染和疾病严重程度的时间,对于患者的安全至关重要.
研究的目的:
- 为了确定选择性手术前的COVID-19诊断是否会影响术后妄想 (POD) 的风险.
- 评估COVID-19和COVID-19疾病严重程度后的外科手术时间对POD发展的具体作用.
主要方法:
- 一项观察性队列研究的二次分析,包括接受选择性非心脏手术的成年患者.
- 用多变量逻辑回归模型来分析数据.
- 与COVID-19诊断 (N=605) 和COVID-19严重程度 (N=573) 相比,评估的手术时间作为POD的预测因素.
主要成果:
- 在COVID-19诊断后7周内进行手术,与COVID-19阴性患者相比,POD风险显著增加 (aOR3.33).
- 有症状的COVID-19感染,而不是无症状的感染,与POD的更高风险相关 (aOR 3.31).
- 最近 (<7周) 症状性COVID-19和手术的综合风险增加了POD风险,特别是在65岁以下的患者中.
结论:
- 手术前的COVID-19,特别是手术后7周内出现症状的病例,与术后妄想症的风险增加有关.
- 需要进一步的研究来确认术前COVID-19和其他术后神经复杂症之间的关联.
更多相关视频
08:17A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
Published on: February 27, 2018
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
相关概念视频
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Peripheral Artery Disease V: Postoperative Nursing Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
