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Updated: Jan 7, 2026

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DNA甲基化塑造了超出规范CpG背景的转录因子结合

Irina Miodownik1, Ruben Solozabal2, Michael P O'Hagan1

  • 1Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.

Proceedings of the National Academy of Sciences of the United States of America
|December 17, 2025
PubMed
概括

细胞因子甲基化影响转录因子 (TF) 的结合. 这项研究揭示了TFs与非CpG和半甲基化DNA的结合方式不同,揭示了新的表观遗传调节机制.

关键词:
表观遗传调节 表观遗传调节叉头蛋白质 叉头蛋白质 是一种半甲基化 半甲基化非CpG甲基化的非CpG甲基化.转录因子结合特异性的特异性

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