在结直肠癌中,Liprin-α1通过激活mTORC2-AKT1通路来增强PHLDB3的致癌功能

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Hyun Min Ko1, Bo Cao1, Li Li2

  • 1Department of Biochemistry & Molecular Biology and Tulane Cancer Center, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.

Cell reports
|December 17, 2025
PubMed
概括

研究人员发现了一种涉及Liprin-α1和PHLDB3的新信号通路,通过激活AKT1信号来驱动结直肠癌 (CRC) 的生长. 这一途径代表了CRC治疗的潜在新疗法标.

关键词:
一个AKT1一个AKT1CP: 癌症 癌症 癌症利林-α1α1 的使用.PHLDB3 PHLDB3 在线播放里克托尔是什么意思和CRC,以及CRC和CRC.在 mTORC2 中,mTORC2 是

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