整体实践:维生素D如何在慢性疼痛管理中发挥作用
Christina N Brown1, Karen Laster1, Cary Springer1
1University of Tennessee - Knoxville, USA.
概括
维生素D补充剂显著降低了患者的慢性疼痛强度和干扰. 这种综合性方法提供了一个非阿片类药物替代品,改善生活质量.
科学领域:
- 综合医学是一个整体的医学.
- 护理实践 护理实践
- 营养科学 营养科学
背景情况:
- 慢性疼痛影响超过1亿美国人,需要非阿片类药物治疗选择.
- 整体护理强调全人护理和基于证据的非药物干预.
- 维生素D缺乏是常见的,可能与慢性疼痛疾病有关.
研究的目的:
- 探索维生素D补充作为一种综合性,非阿片类药物治疗慢性疼痛的方法.
- 评估维生素D对疼痛强度,疼痛干扰和血清水平的影响.
- 为了提高质量,与约翰霍普金斯护理基于证据的实践模型 (JHEBP) 保持一致.
主要方法:
- 一个为期12周的质量改进项目,涉及30名以前没有服用过维生素D的慢性疼痛患者.
- 参与者每周接受口服剂量为5万IU的维生素D.
- 结果通过前后调查,临床评估和血清维生素D水平测试来衡量.
主要成果:
- 疼痛强度 (p=0.007) 和疼痛干扰 (p=0.020) 的统计显著减少.
- 血清维生素D水平从24增加到36ng/mL (p<0.001),效应大小很大 (科恩d=1.28).
- 91%的参与者报告说,从补充中获得主观益处.
结论:
- 维生素D补充可以成为整体慢性疼痛管理的宝贵组成部分.
- 这种方法支持减少对阿片类止痛药的依赖.
- 纳入维生素D促进了整合性护理实践,并促进了公平的患者护理.
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