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在患有多发性硬化症的患者中,Treg对克拉迪宾诱导的衰竭的敏感性与治疗反应相关

Ilenia Cammarata1,2, Giorgia Sartori1, Tiziano Giacomelli1,2

  • 1Department of Translational and Precision Medicine, Sapienza University of Rome, Italy.

Neurology(R) neuroimmunology & neuroinflammation
|December 17, 2025
PubMed
概括

对多发性硬化症 (MS) 的克拉迪宾治疗可能由于耐性休息调节性T细胞 (Tregs) 的存在,效果较差. 这些休息的Tregs通过表达抗亡蛋白质来抵抗枯竭,这可能会阻碍免疫耐受性恢复.

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