区分尾炎严重程度中的NLR和PLR:一个元分析
Kaijun Li1, Junjie Xiang1, Yuqian Li1
1School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China.
The Journal of surgical research
|December 17, 2025
概括
中性粒细胞与淋巴细胞的比率 (NLR) 在诊断复杂尾炎时比血小板与淋巴细胞的比率 (PLR) 更有效. 这一发现有助于为腹痛管理做出早期临床决定.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 炎症生物标志物 炎症生物标志物
- 胃肠病学 胃肠病学
背景情况:
- 诊断急性尾炎需要区分简单和复杂的形式,以有效治疗.
- 目前的诊断方法,如成像和评分系统,在准确性上有局限性.
- 中性细胞与淋巴细胞的比率 (NLR) 和血小板与淋巴细胞的比率 (PLR) 正在成为可访问的炎症标志物.
研究的目的:
- 评估NLR和PLR在区分简单和复杂尾炎的诊断准确性.
- 评估这些比率在不同年龄组 (儿科和成人) 的有效性.
- 为了比较NLR与PLR在临床决策中的可靠性.
主要方法:
- 对2025年5月之前发表的研究进行系统的文献搜索.
- 使用接收器操作特征 (ROC) 曲线分析对诊断准确性的元分析.
- 结果按年龄组分层 (儿科和成人).
主要成果:
- 在整个人群中,NLR表明复杂尾炎诊断的曲线下 (AUC) 的聚合面积为0.76.
- 根据年龄分层分析显示,儿童和成人组的NLR表现一致 (AUC为0.74).
- PLR的聚合AUC较低,为0.67,聚合灵敏度为0.58和特异性为0.69.
结论:
- 对于识别复杂尾炎,NLR比PLR更可靠的生物标志物.
- 这些发现支持NLR在指导尾炎早期临床决策方面的实用性.
- NLR为改善尾炎诊断提供了一种有价值,具有成本效益的工具.
相关概念视频
01:29Appendicitis-II: Diagnostic Studies and Management
461
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
461
01:22Appendicitis-I: Introduction
2.1K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
2.1K