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Updated: Aug 1, 2026

A Standardized Approach for Multispecies Purification of Mammalian Male Germ Cells by Mechanical Tissue Dissociation and Flow Cytometry
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A Standardized Approach for Multispecies Purification of Mammalian Male Germ Cells by Mechanical Tissue Dissociation and Flow Cytometry

Published on: July 12, 2017

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磁性激活细胞分类 无细胞灭绝的精子选择 改善DNA碎片化和生殖结果:系统性审查和元分析

Mar Falquet Guillem1, Rosa Pacheco1, Alma Gisbert-Iranzo1

  • 1IVIRMA Global Research Alliance, IVI Foundation, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.

Reproductive biomedicine online
|December 17, 2025
PubMed
概括

磁激活细胞分类 (MACS) 可以减少精子DNA碎片化,但不能改善人工授精的结果. 然而,MACS在细胞体内精子注射中有望改善妊娠和活产率,特别是在具有高DNA碎片化的患者中.

关键词:
在DNA碎片化过程中,DNA碎片化.磁激活细胞分类 磁激活细胞分类生殖结果的结果.精子选择精子选择

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Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...