手术前对大麻素的暴露和手术后的疼痛:一个叙述性回顾
Daniel D King1, Rhea Temmermand2, Jennifer E Greenwood1
1Department of Nurse Anesthesia, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Journal of clinical anesthesia
|December 17, 2025
概括
手术前使用大麻可能会增加术后疼痛和阿片类药物需求,尽管结果因手术专业而异. 需要进一步的研究来明确术后疼痛管理策略.
科学领域:
- 麻醉学和疼痛管理
- 药理学 药理学是指药理学的学科.
- 手术结果研究研究.
背景情况:
- 大麻使用量正在上升,但其对急性外科手术期间疼痛和阿片类药物消费的影响尚不清楚.
- 现有的关于治疗慢性疼痛的大麻素的研究尚未完全转化为外科手术期间的环境.
研究的目的:
- 系统地审查有关手术前大麻使用及其与术后疼痛和阿片类药物需求的相关文献.
- 识别不同外科专业的结果的模式和变化.
主要方法:
- 在PubMed,CINAHL和Embase进行了系统的文献搜索,寻找过去十年发表的研究.
- 包括42项研究,研究了手术前大麻使用及其与术后疼痛和阿片类药物消费的关系.
- 由于研究设计和结果措施的异质性,数据使用叙事方法进行了合成.
主要成果:
- 很大一部分研究 (33.3%) 报告大麻使用者手术后疼痛增加,而23.8%没有发现差异.
- 在42.9%的研究中,大麻使用者的阿片类药物需求更高,其中40.5%报告没有差异.
- 根据专业出现了模式:脊柱手术更频繁地显示了阿片类药物使用的增加,而关节整形研究经常报告没有差异.
结论:
- 在手术前暴露于大麻与某些手术环境中的术后疼痛和阿片类药物需求增加有关,但并非普遍存在.
- 跨专业结果的变化和研究设计的局限性需要标准化的定义和前性研究.
- 个性化的术后疼痛管理策略至关重要,考虑到患者特定的因素,如大麻使用.
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