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Updated: Jan 8, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
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Published on: June 26, 2018

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类基因映射揭示了15种自身免疫性疾病的共享免疫调节枢纽

Yi Jin1, Hui-Min Lu2, Xing-Hao Yu3

  • 1Wujin Hospital Affiliated with Jiangsu University, Changzhou 213017, Jiangsu, China; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou 221002 Jiangsu, China; The Wujin Clinical College of Xuzhou Medical University, Changzhou 213017, Jiangsu, China.

Human immunology
|December 17, 2025
PubMed
概括

这项研究揭示了15种自身免疫性疾病 (AID) 的共同遗传因素,确定了关键的类基因,如SKIV2L,HCP5和NOTCH4. 这些发现将主要组织相容性复合体 (MHC) 区域与免疫细胞通路联系起来,有助于生物标志物和治疗开发.

关键词:
自身免疫性疾病是一种自身免疫性疾病.遗传上的重叠是遗传上的重叠.免疫调节 免疫调节门德尔的随机化类基因的基因是类基因.

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