相关实验视频

Updated: May 8, 2026

Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
08:16

Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus

Published on: June 17, 2015

19.0K

过多的铁可能会加速老老鼠大脑中的粉样β积累

Soo-Jin Song1, Jung-A Shin1

  • 1Department of Anatomy, College of Medicine, Ewha Womans University, Seoul 07804, South Korea.

Neurobiology of aging
|December 17, 2025
PubMed
概括

系统性铁过载可能会加速大脑衰老中的粉样β (Aβ) 病理,增加Aβ聚合并影响认知功能. 这表明铁过载会加剧与年龄相关的大脑变化.

关键词:
衰老的衰老 衰老的衰老氨基βββββββββββββββββββββββββ大脑大脑大脑的大脑大脑铁过载是什么?铁过载是什么?神经退行性疾病的神经退行性疾病

更多相关视频

Detecting Amyloid-β Accumulation via Immunofluorescent Staining in a Mouse Model of Alzheimer's Disease08:25

Detecting Amyloid-β Accumulation via Immunofluorescent Staining in a Mouse Model of Alzheimer's Disease

Published on: April 19, 2021

3.9K
Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining07:32

Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

Published on: May 23, 2025

1.0K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...