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Updated: Jan 8, 2026

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
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定义了1900年至1908年因子VIII残留在因子VIIIa-因子IXa复合物的形成和因子VIIIa活性中的关键作用

Haixia Lv1, Zhe Ming2, Dongmei Wang2

  • 1College of Life Science, State Key Laboratory Cell Differentiation and Regulation and Henan International Joint Laboratory for Pulmonary Fibrosis, Henan Normal University, Xinxiang, Henan, China; Pharmacy College, Xinxiang Medical University, Xinxiang, Henan, China.

Journal of thrombosis and haemostasis : JTH
|December 17, 2025
PubMed
概括

在因子 (F) VIIIa区域1900-1908中的特定突变显著损害了其辅因子活性和对FIXa的结合亲和力. 这些发现澄清了这些残留物在FXase复合物的稳定性和功能中的作用.

关键词:
衰变速度的衰变速度是多少第九个因子Xa因子这就是VIIIa因子.产生XA因子的XA因子.光异性异性异性异性异性

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