持续的脑电图监测在儿科重症监护室中的实用性和预后影响
Alper Koker1, Furkan Donbaloğlu2, Erdem Çebişli1
1Division of Pediatric Intensive Care, Department of Pediatrics, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Neuropediatrics
|December 17, 2025
概括
在儿科重症监护室 (PICU) 中,持续电脑电图 (cEEG) 有助于发作的检测和治疗调整. 然而,很大一部分儿童长期患有耐药性 (DRE),这凸显了进一步研究的必要性.
科学领域:
- 神经科学是一个神经科学.
- 儿科重症监护中心儿童重症监护中心
- 临床神经生理学 临床神经生理学
背景情况:
- 持续脑电图 (cEEG) 的使用在儿科重症监护室 (PICU) 正在增加,但其在重症儿童的诊断和预后价值需要更多的数据.
- 了解EEG监测实践,发作检测率和治疗影响对于优化儿科神经临床环境的护理至关重要.
研究的目的:
- 评估EEG监测实践,包括间歇性EEG和cEEG,在第三级PICU.
- 评估EEG在检测发作,指导抗治疗修改和识别非状态 (NCSE) 中的诊断产量.
- 为了确定长期的结果,特别是药物耐药性 (DRE) 的发展,在重症儿童.
主要方法:
- 从2018年到2022年,对184名儿童 (1个月至18岁) 的回顾性分析,这些儿童从2018年到2022年在第三级PICU中接受了间歇性EEG或cEEG.
- 收集的数据包括人口统计和临床特征,EEG指示,发现,抗治疗变化和患者结果.
- 评估的主要结果是急性控制,NCSE的发生和随访期间DRE的发展.
主要成果:
- 在12.0%的患者中检测到电图发作,导致77.3%的患者改变抗发作疗法.
- 在2.7%的患者中发现了以前未被怀疑的非性发作;在98.0%的患者中实现了急性发作控制.
- 在平均8.0个月的随访期间,20.7%的患者被新诊断为DRE,特别是那些患有急性脑病变,缺氧缺血损伤或中枢神经系统感染的患者.
结论:
- 脑电图,特别是高危儿科患者的脑电图 (cEEG),为在PICU中电图发作检测和抗发作管理提供了宝贵的信息.
- 该研究发现,在这个儿科PICU队列中,DRE的长期负担显著.
- 有必要进行前性的多中心研究,以确定EEG在儿科神经临床护理中的最佳作用.
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