抗生素副作用和过敏对患者坚持和态度的影响:英格兰的一项混合方法研究
Liam Michael Clayton1, Catherine V Hayes1, Luke O'Neill1
1Primary Care and Interventions Unit, UK Health Security Agency, England, UK.
BJGP open
|December 17, 2025
概括
抗生素的副作用会影响患者的行为,导致许多人过早停止治疗. 改善沟通和对过敏的重新评估对于适当使用抗生素和打击抗菌素耐药性至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者行为研究 患者行为研究
- 公共卫生 公共卫生
背景情况:
- 滥用抗生素可以促进抗菌素耐药性 (AMR).
- 虽然已知抗生素的不良反应,但它们对患者行为的影响需要更多的研究.
研究的目的:
- 调查抗生素副作用和过敏如何影响患者对处方抗生素使用的行为.
主要方法:
- 英国的一项混合方法研究,涉及对1059名成年人和21名参与者聚焦小组的调查.
- 用描述性统计,奇二次测试和主题分析来分析数据.
主要成果:
- 许多患者经历了破坏性的抗生素副作用.
- 三分之一的人不知道由于信息获取不佳而导致的潜在副作用.
- 近一半的人在经历副作用后没有完成抗生素疗程,许多人在没有医疗建议的情况下停止治疗.
结论:
- 抗生素的副作用显著影响患者,并可能导致不适当的使用,导致AMR.
- 建议加强患者信息和重新评估过敏标签,以改善抗生素坚持和管理.
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