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Updated: Jan 8, 2026

Reverse Genetics to Engineer Positive-Sense RNA Virus Variants
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Reverse Genetics to Engineer Positive-Sense RNA Virus Variants

Published on: June 9, 2022

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通过TIAR转录脱离SARS-CoV-2 Nsp1-介导宿主关闭揭示了Nsp1耐药性的一般特征

Caleb Galbraith1, Madeleine Stolz1, Scott Tersteeg2

  • 1Dalhousie University Faculty of Medicine.

RNA (New York, N.Y.)
|December 17, 2025
PubMed
概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 非结构蛋白1 (Nsp1) 抑制宿主基因表达. 我们发现,TIAR 5'非翻译区域 (UTR) 中的特定序列对Nsp1主机关闭产生抗性.

关键词:
在LARP1中使用LARP1.在 Nsp1 中使用.蒂亚尔 (Tiar) 是一个象牙.冠状病毒冠状病毒病毒主机关闭 的主机关闭

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