相关实验视频

Updated: Jan 8, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
06:38

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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由于PCK1缺乏,MASH-HCC通过12-HETE诱导的CD8+ T细胞功能障碍进展

Kang Wu1, Luo Li2,3, Yi Liu4

  • 1Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Gut
|December 17, 2025
PubMed
概括

烯酸碳素激酶1 (PCK1) 对于与代谢功能障碍相关的肝炎相关的肝细胞癌 (MASH-HCC) 治疗至关重要. 恢复PCK1或抑制12-HETE可以提高抗PD-1治疗对MASH-HCC的有效性.

关键词:
致癌的新陈代谢脂肪的肝脏的脂肪肝细胞癌细胞癌症

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Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer08:34

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相关概念视频

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Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
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