在德国 (DINKS) 为女性尿失禁患者提供基于应用程序的治疗:单盲,随机,受控试验
Axel Haferkamp1, Lisa Frey1, Gregor Duwe1
1Department of Urology and Pediatric Urology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
The Lancet. Digital health
|December 17, 2025
概括
一个基于应用程序的疗法显著减少了60%的女性尿失禁事件,当添加到标准护理. 这种数字治疗方法为管理失禁和弥合治疗差距提供了一个有前途的解决方案.
科学领域:
- 数字治疗学数字治疗学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 妇女健康 妇女健康
背景情况:
- 尿失禁影响了相当一部分成年女性.
- 尿失禁的保守治疗方法往往未得到充分利用.
- 基于应用程序的数字疗法显示出改善治疗可访问性的潜力.
研究的目的:
- 评估基于应用程序的数字治疗药物的有效性,作为尿失禁标准护理的辅助.
- 为了确定该干预措施是否与标准护理相比显著降低了失禁事件的频率.
主要方法:
- 在德国进行了一项为期12周的单盲随机对照试验.
- 参与者 (N=194) 患有每日失禁情节被随机分配到基于应用程序的治疗加上通常的护理或仅仅是通常的护理.
- 主要终点是每日失禁事件频率的相对变化,通过3天的电子日记进行测量.
主要成果:
- 干预组在失禁发作中实现了60.95%的平均相对减少,而对照组的1.69% (p<0.0001).
- 在干预组中观察到临床相关的失禁频率减少 (≥50%).
- 没有报告与治疗相关的重大不良事件.
结论:
- 基于应用程序的治疗,当与标准护理相结合时,可以有效地减少尿失禁事件的频率.
- 这种数字疗法证明了解决尿失禁管理治疗缺口的潜力.
- 这些发现支持将基于应用程序的干预措施纳入尿失禁的常规临床实践.
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