激素替代疗法对绝经后妇女声乐基本频率的影响
Anuja H Shah1, Stephanie Horton2, Nathaniel L Baker3
1Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina; Georgetown University School of Medicine, Washington, District of Columbia.
Journal of voice : official journal of the Voice Foundation
|December 17, 2025
概括
女性的基本声频 (F0) 随着年龄的增长而下降. 含激素的激素替代疗法 (HRT) 在绝经后妇女中没有显著影响F0.
科学领域:
- 内分泌学 在内分泌学.
- 喉腔病理学 喉腔病理学
- 老年学是指老年学的学科.
背景情况:
- 在更年期期间可能会发生声乐变化.
- 激素波动会影响各种生理过程,包括声音特征.
研究的目的:
- 调查前更年期和更年期后妇女之间的声音基本频率 (F0) 差异.
- 检查F0与年龄和激素使用的关联,包括雌激素-孕激素治疗与替代疗法 (EPT-HRT) 和避孕药 (BC).
主要方法:
- 这是一项涉及四组人群的横截面研究:接受EPT-HRT的绝经后妇女,不接受HRT的绝经后妇女,接受BC的绝经前妇女和不接受BC的绝经前妇女.
- 测量声F0 (以赫兹) 并在各组之间进行比较.
- F0与年龄等人口统计学变量相关.
主要成果:
- 在经期绝经后的妇女与没有EPT-HRT之间,或在经期绝经前的妇女与没有BC之间没有发现显著的F0差异.
- 与两个更年期前组相比,EPT-HRT治疗的绝经后妇女的平均F0较低.
- 观察到年龄和F0之间的中度负相关性 (r = -0.39,P < 0.001).
结论:
- 随着年龄的增长,女性的基本声频 (F0) 降低.
- 含激素的激素替代疗法 (HRT) 在本研究人群中没有对F0产生显著影响.
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