低收入和中等收入国家的避孕药诱导的月经变化:一个系统的范围审查
Maureen Makama1,2, Annie R A McDougall3,4, Jenny Jung3
1Women's, Children's and Adolescents' Health Program, Burnet Institute, Melbourne, VIC, Australia. maureen.makama@burnet.edu.au.
Communications medicine
|December 17, 2025
概括
避孕药诱导的月经变化 (CIMCs) 是常见的,导致中止,无法满足避孕的需要. 标准化定义和新疗法对于改善低收入和中等收入国家的护理至关重要.
科学领域:
- 生殖健康 生殖健康
- 全球健康 全球健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 避孕产生的月经变化 (CIMCs) 显著影响避孕的满意度和持续率.
- 综合了关于低收入和中等收入国家 (LMICs) 的CIMC流行,健康影响,治疗和获取障碍的证据.
研究的目的:
- 总结关于LMICs中避孕药诱导的月经变化的现有证据.
- 发现关于CIMC流行,影响,治疗和获取的研究缺口.
主要方法:
- 系统地搜索9个数据库 (2000-2024) 在LMIC中对现代避孕药使用者的研究 (不包括屏障/永久方法).
- 使用世卫组织贝尔西的出血频率和严重性的定义来对发现进行分类.
- 定量数据的描述性统计和定性数据的专题综合.
主要成果:
- 包括来自44个国家的321项研究,显示CIMC患病率在0-94%之间,根据避孕类型而异.
- 在40.2%的流行报告中缺乏标准化的CIMC定义.
- 停用避孕药和未满足的避孕需求是主要的健康影响;NSAID是最受研究的治疗方法. 没有关于治疗准入障碍的研究报告.
结论:
- CIMCs对避孕药使用者的影响不同,强调需要改进咨询.
- 标准化的CIMC定义对于提高初级研究数据质量至关重要.
- 需要投资于新型治疗方法和方法,以满足CIMC产生的未满足的避孕需求.
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