左心房-心室合指数与ST段升高心肌梗塞患者的新发性心房动相关
Jiahua Liu1, Xinjia Du1, Jingfang Zhou1
1Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
BMC cardiovascular disorders
|December 17, 2025
概括
左心房-心室合指数 (LACI) 独立地与ST段升高心肌梗塞 (STEMI) 患者的新发性心房动 (NOAF) 相关. 结合LACI可以更好地识别PCI后NOAF风险较高的患者.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 电子生理学 电子生理学
背景情况:
- 在ST段升高心肌梗塞 (STEMI) 患者中治疗新发性心房动 (NOAF) 具有临床挑战.
- 左心房-心室合指数 (LACI) 是一个新兴的心血管风险标志物.
- 在STEMI患者中,LACI和NOAF之间的关联尚未得到充分证实.
研究的目的:
- 通过心磁共振 (CMR) 测量的LACI与STEMI患者中NOAF皮肤穿刺后冠状动脉干预 (PCI) 的发生之间的关系.
主要方法:
- 一个回顾性,单中心研究从2018年9月到2024年12月招募了接受CMR的STEMI患者.
- LACI的计算是左心房末端透缩体积指数与左心室末端透缩体积指数的比率.
- 进行了多变量逻辑回归和ROC曲线分析.
主要成果:
- 在553名STEMI患者中,有46名患有NOAF.
- LACI (OR=1.10),微血管阻塞 (OR=1.16) 和心率 (OR=1.03) 是NOAF的独立风险因素.
- LACI表现出良好的预测性能 (AUC=0.733) 并显著改善了NOAF风险预测模型.
结论:
- 在STEMI患者中,LACI是PCI后NOAF的独立预测因子.
- 将LACI整合到风险评估模型中可以提高对NOAF风险较高的患者的识别.
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