电子健康干预措施随机对照试验的元分析,以减少药物错误
Michelle Natasha Colin1, Salma Tri Octaviany1, Michelle Darmawan1
1Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
NPJ digital medicine
|December 17, 2025
概括
电子干预显著减少医疗保健中的药物错误. 计算机化决策支持系统 (CDS) 在提高患者安全和预防药物不良事件 (ADEs) 方面表现特别有效.
科学领域:
- 医疗信息学 医疗信息学
- 患者安全 患者安全
- 临床药房 临床药房
背景情况:
- 药物错误在医疗保健中是一个关键的安全问题,包括潜在和实际事件.
- 实际错误可能导致药物不良事件 (ADEs),影响患者的治疗结果.
- 电子干预越来越多地被探索以减轻这些风险.
研究的目的:
- 与常规护理相比,系统地审查和元分析电子干预措施在减少药物错误方面的有效性.
- 评估这些干预措施对整体患者安全的影响.
主要方法:
- 在 EBSCO,Embase,PubMed 和 Web of Science 数据库中进行了系统的文献搜索.
- 随机对照试验 (RCT) 被选择和分析,在解决异质性后包括了9项研究.
- 用元分析来确定电子干预的整体效果.
主要成果:
- 电子干预与统计学上显著的15%的药物错误风险降低有关 (RR = 0.85;95%CI:0.77-0.94).
- 小组分析表明,计算机化决策支持系统 (CDS) 特别有效.
- 这些发现支持电子系统在提高药物安全方面的作用.
结论:
- 集成电子系统,特别是CDS,为提高药物安全提供了一个有前途的战略.
- 需要进一步的研究来证实这些好处在不同的医疗保健环境.
- 这些发现为采用电子解决方案减少药物错误提供了基于证据的支持.
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