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Updated: Jan 8, 2026

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在结核性脑膜炎中使用德克萨米他的药理动力学

Jose M Calderin1, Juan Eduardo Resendiz-Galvan1, Noha Abdelgawad1

  • 1Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, Cape Town, South Africa.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
|December 17, 2025
PubMed
概括

高剂量里法辛在结核性脑膜炎 (TBM) 患者中没有改变德克萨米他的暴露. 药物相互作用,特别是lopinavir/ritonavir,在与HIV相关的TBM中显著增加了德甲清除.

关键词:
德克萨米他是一种药物相互作用 药物相互作用药物动力学 药物动力学这种药物是里法皮辛 (rifampicin).结核性脑膜炎是一种

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