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Updated: Jan 8, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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托尔类受体激素对人类CD8+T细胞激活和T细胞检查点受体表达的影响

Donghwan Jeon1, Jena E Moseman1, Ethan Hill1

  • 1Department of Medicine, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.

Human vaccines & immunotherapeutics
|December 18, 2025
PubMed
概括

收费类受体 (TLR) 激动剂,特别是TLR3激动剂,可以增强人类CD8+T细胞的激活. 这表明TLR3激动剂可能是针对抗原特异性CD8+T细胞的癌症疫苗和免疫疗法的宝贵辅助剂.

关键词:
在 CD8+ T 细胞中.在PD-1中使用PD-1.T细胞检查点受体受体的检查点.这是一种TLR激动剂.

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