全免疫-炎症值作为隔离冠状动脉狂热的独立指标
Çağatay Tunca1, Mehmet Taha Özkan2, Berin Nur Ergin1
1Department of Cardiology, Ankara Etlik City Hospital, Ankara, Türkiye.
概括
全免疫-炎症值 (PIV) 与冠状动脉抽血 (CAE) 相关,这是一种炎症性血管疾病. 更高的PIV水平可能有助于识别患有CAE风险的患者.
科学领域:
- 心脏病学 心脏病学
- 血管生物学 血管生物学
- 炎症研究 炎症研究
背景情况:
- 冠状动脉脱动 (CAE) 越来越多地被理解为一种活跃的炎症性血管疾病.
- 全免疫炎症值 (PIV) 是一种新的生物标志物,通过血液细胞计数反映系统性炎症.
研究的目的:
- 调查PIV和CAE之间的关联.
- 为了比较PIV的诊断性能与CAE的传统炎症标志物.
主要方法:
- 一项回顾性病例对照研究包括228名CAE患者和296名对照患者.
- 分析了冠状动脉血管学数据和血液学参数.
- 后勤回归和ROC分析评估了PIV的预测价值.
主要成果:
- 患有CAE的患者的PIV水平明显高于对照组 (P < 0.001).
- PIV与CAE独立相关 (OR: 1.987,P = 0.033) 并显示出优越的辨别能力 (AUC: 0.674).
- PIV与其他炎症指数如SII,NLR,PLR和SIRI有很强的相关性.
结论:
- 升高的PIV水平与CAE独立相关,突出显示了系统性炎症的作用.
- PIV可以作为一种实用的,可访问的标记,用于识别CAE风险患者.
相关概念视频
Pericarditis II: Clinical Features and Diagnostic Tests
262
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
262
Acute Coronary Syndrome I: Introduction
711
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
711
Acute Coronary Syndrome III: Diagnostic Studies
197
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
197
Myocarditis I: Introduction
341
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
341


