在患有物质使用障碍的患者中重复处方模式
Johannes Heck1, Benjamin Krichevsky2,3, Martin Schulze Westhoff4
1Institute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
Pharmacology research & perspectives
|December 18, 2025
概括
潜在不适当的重复处方 (PIDPs) 发生在12.8%的患有物质使用障碍的精神病患者中. 镇静剂和阿片类药物是常见的原因,强调需要仔细监测药物,以防止药物不良反应.
科学领域:
- 药理学 药理学是指药理学的学科.
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 复制处方 (DPs) 是患者护理中的一个问题.
- 将DP分为适当的 (ADP) 和可能不适当的 (PIDP) 是评估药物安全性的关键.
- 患有物质使用障碍 (SUD) 的患者通常有复杂的药物治疗方案,增加了DP的风险.
研究的目的:
- 确定患有SUD的精神病医院住院患者中PIDPs的频率和特征.
- 在这个患者群体中区分ADP和PIDP.
- 确定与PIDPs相关的常见药物类别.
主要方法:
- 在一所大学医院的成病房对1174名患者进行了回顾性横截面研究.
- 从2016年1月到2021年12月的药物记录分析.
- 将DP分为ADP和PIDP的分类 (等级1-3).
主要成果:
- 12.8%的患者至少经历过一次PIDP.
- 最常见的是1级PIDPs (12.0%),主要涉及镇静剂.
- 2级PIDPs (1.3%) 主要与阿片类药物有关.
- 29.0%的患者至少有一次ADP.
结论:
- 潜在不适当的重复处方在患有SUD的精神病患者中很普遍.
- 镇静剂和阿片类药物是导致PIDPs的关键药物类别.
- 对PIDP的警监测对于改善患者安全和降低医疗保健成本至关重要.
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