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Updated: Jan 8, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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Published on: February 27, 2016

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通过减少的尼古丁酸 рибоoside (NARH) 对SIRT5活性进行差异调节

Abu Hamza1, Dickson Donu1, Emily Boyle1

  • 1Department of Medicinal Chemistry, Virginia Commonwealth University Richmond VA 23219 USA ceny2@vcu.edu +1 804-828-7405.

RSC chemical biology
|December 18, 2025
PubMed
概括

研究人员确定了减少的尼古丁酸 рибоoside (NARH) 作为SIRT5.5的新型调节器. 这种化合物通过差异调节SIRT5活动,为开发针对各种疾病的SIRT5激活剂提供了一个新的支架.

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