多发性骨髓瘤呈现为巨大的骨解性头骨质量:手术挑战和陷 - 一个案例报告
Shahd H I Abbastanira1, Modar Mouhsen Monther2, Muhammad Mukhtar Khan2
1Department of Emergency Medicine, Dubai health, Dubai, United Arab Emirates.
Surgical neurology international
|December 18, 2025
概括
多发性骨髓瘤 (MM) 的巨型头骨病变很少见,但具有攻击性. 这一案例凸显了需要及时诊断和多学科护理,包括手术和全身治疗,以在这些具有挑战性的演示中获得最佳结果.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 骨解性头骨病变有多种不同的原因,多发性骨髓瘤 (MM) 是成年人的重大恶性病因.
- 虽然骨参与在MM中很常见,但具有广泛破坏和内延伸的巨型外生病变非常罕见.
研究的目的:
- 报告一个罕见的巨型外生性头骨损伤的病例,这是多发性骨髓瘤的次要病例.
- 强调这种罕见的呈现所带来的诊断和治疗挑战.
主要方法:
- 一名48岁的男性患有进展性神经缺陷,接受了高级成像 (CT,MRI) 和手术切除.
- 组织病理学,免疫组织化学,PET-CT和骨髓活检证实了疾病的诊断和系统性.
主要成果:
- 确定了一种大型的,具有破坏性的左前双关节病变,具有显著的内延伸和质量效应.
- 诊断证实了一种高度恶性血细胞瘤与MM一致,系统性疾病明显.
结论:
- 在MM中,巨型外生性头骨病变很少见,模仿其他瘤并呈现诊断困难.
- 早期识别,全面检查和涉及激进手术切除和全身治疗的多学科方法对于管理这些侵袭性病例至关重要.
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