通过CAP-PRI对活跃慢性炎症性脱叶林性多基基隆性神经病症患者的生命质量和功能长度评估
Ivo Bozovic1, Kelly Gwathmey2, Stojan Peric1,3
1University Clinical Center of Serbia-Neurology Clinic, Belgrade, Serbia.
Journal of the peripheral nervous system : JPNS
|December 18, 2025
概括
慢性获得性多神经病患者报告指数 (CAP-PRI) 可靠地测量活跃的慢性炎症性脱细林性多神经病 (CIDP) 患者的生活质量 (QoL). 这种工具对于随着时间的推移监测疾病进展是敏感和有效的.
科学领域:
- 神经学 神经学
- 临床研究 临床研究
- 患者报告的结果
背景情况:
- 一般的生活质量 (QoL) 调查问卷对于慢性炎症性脱叶林性多基基隆性神经病 (CIDP) 往往是不够的.
- 慢性获得性多神经病患者报告指数 (CAP-PRI) 是针对慢性免疫媒介多神经病的.
研究的目的:
- 在使用CAP-PRI的活跃CIDP患者中纵向评估QoL和功能.
- 与其他措施相比,评估CAP-PRI的可靠性和敏感性.
主要方法:
- 57名活跃的CIDP患者在基线,第一年和第四年被评估.
- 在所有时间点中,CAP-PRI与MRC-SS,INCAT,I-RODS和SF-36一起使用.
主要成果:
- CAP-PRI与损伤和残疾措施 (MRC-SS,INCAT,I-RODS,SF-36) 有着强烈的相关性.
- CAP-PRI在改善和恶化的患者之间进行了区分,并在第一年和第四年表现优于SF-36.
- CAP-PRI的变化与损伤和残疾分数的变化相关.
结论:
- CAP-PRI是评估活跃CIDP患者的QOL的可靠和敏感工具.
- CAP-PRI的持续表现支持其在临床监测和研究中用于活跃的CIDP.
相关概念视频
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
318
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
318
Peripheral Artery Disease IV: Nursing Management
316
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
316
Assessment of the Cardiovascular System III: Palpation
968
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
968
Peripheral Artery Disease III: Interprofessional Care
221
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
221
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
3.1K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
3.1K
Peripheral Artery Disease I: Introduction
288
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
288


