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线粒体功能障碍驱动氧化应激和能量失衡 在脊柱关节炎的小鼠模型中

Rodrigo Prieto-Carrasco1, Susana Aideé González-Chávez1, Eduardo Chaparro-Barrera1

  • 1PABIOM Laboratory, Faculty of Medicine and Biomedical Sciences, Autonomous University of Chihuahua, Chihuahua, Mexico.

Cell biochemistry and function
|December 18, 2025
PubMed
概括

线粒体功能障碍导致脊椎关节炎 (SpA) 的关节损伤. 这项研究揭示了SPA中线粒体动态的改变,能量生产的减少和氧化应激的增加,这表明新的治疗点.

关键词:
在 DBA/1 小鼠.线粒体中的线粒体.线粒体的动力学线粒体功能障碍 线粒体功能障碍线粒体的周转率氧化应激是一种氧化应激.脊柱性关节炎 (spondyloarthritis) 是一个疾病.

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