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Updated: Jan 8, 2026

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
09:06

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

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通过向LOX-1减少动脉硬化斑块的形成

Jie Zhang1, Liwen Yu1, Wei Yang1

  • 1State Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China (J.Z., L.Y., W.Y., L.C., X. Wang, C.K., Z.L., R.R., W.Q., L.L., W.X., W.S., X. Wu, N.L., B.L., S.W., P.B., Y.Z., C.Z., M.Z.).

Circulation
|December 18, 2025
PubMed
概括

通过降解巨细胞中的甲酸样氧化低密度脂蛋白受体-1 (LOX-1) 来防止动脉样硬化. 这减少了泡细胞的形成和炎症,这表明TRIM31是治疗点.

关键词:
动脉样硬化泡细胞炎症的发生巨细胞无处不在

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