英格兰晚期艾滋病毒诊断的危险因素,2015-2023年
Joseph Jasperse1,2, Ross J Harris3, Clare Humphreys4
1UK Field Epidemiology Training Programme, UK Health Security Agency, Newcastle upon Tyne, UK.
HIV medicine
|December 18, 2025
概括
晚期艾滋病毒诊断在英国很常见,特别是在老年人和少数民族中. 有针对性的测试策略对于降低死亡率和传播风险至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病监测 传染病监测 传染病
背景情况:
- 人类免疫缺陷病毒 (HIV) 的晚期诊断与增加的死亡率和进一步传播有关.
- 有效的艾滋病毒检测策略对于减轻这些风险至关重要.
研究的目的:
- 分析与英格兰晚期艾滋病毒诊断相关的风险因素.
- 为制定有针对性的艾滋病毒检测策略提供信息.
主要方法:
- 对15岁以上 (2015-2023) 英格兰居民的国家艾滋病毒监测数据的分析.
- 包括可能性传播艾滋病毒的个人.
- 晚期诊断的定义:在91天内CD4计数<350细胞/毫米3,没有最近感染的证据.
- 多变量后勤回归用于识别风险因素.
主要成果:
- 在18217例艾滋病毒诊断中,有39%的诊断是迟到的.
- 高龄 (aOR:1.44每10年) 是一个显著的风险因素.
- 亚洲 (aOR: 1.69) 和非洲黑人 (aOR: 1.43) 种族的非英国出生的个人有更高的风险.
- 与男性发生性关系的男性 (MSM) 的预测晚诊断概率从21%增加到32% (2015-2023).
结论:
- 优先考虑超越性健康服务的有针对性和可访问的艾滋病毒检测.
- 专注于老年人,通过男性和女性之间的性行为暴露的个人,以及非英国出生的少数民族.
- 这些策略旨在减少晚期诊断和改善健康结果.
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