增加精液微塑性负担在患有静脉的男性:一个受控的临床研究
1Department of Urology, Gülhane Training and Research Hospital, University of Health Sciences, 06010, Etlik, Ankara, Türkiye. yavuzilki@gmail.com.
International urology and nephrology
|December 18, 2025
概括
患有静脉的男性在精液中含有更高的微塑料含量,这与精子质量差有关. 这表明静脉可能会加剧环境微塑料造成的生殖损害.
科学领域:
- 环境健康 环境健康
- 生殖生物学 生殖生物学
- 毒理学 毒理学 毒理学
背景情况:
- 微塑料 (MP) 存在于人体组织中,包括精液,这引发了人们对男性生殖健康的担忧.
- 静脉,男性不孕症的常见原因,涉及氧化应激和丸功能改变,可能促进MP积累.
研究的目的:
- 为了比较有和没有瘤的男性之间的精液微塑性负担.
- 调查精液微塑料负载和精液质量参数之间的关联.
主要方法:
- 一项前性病例控制研究,涉及50名患有静脉的男性和48名对照.
- 按照世卫组织2021年指导方针进行精液分析;微塑料通过显微镜分离和定量.
- 用于评估关联的相关性和多变量逻辑回归.
主要成果:
- 在静脉患者中,精液MP负载显著增加 (中位数为8个与4个颗粒/毫升相比).
- 在84%的静脉样本中检测到MPs,而对照组的62.5%;纤维类型的颗粒占主导地位.
- MP负荷与精子度,渐进的运动性和正常形态学负相关.
结论:
- 精液中的微塑料含量在患有水瘤的男性中升高.
- 较高的微塑料负荷独立地与精子运动率的降低有关.
- 静脉可能会加剧微塑料的生殖毒性.
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