茶和咖啡的摄入量,COPD,成人喘和肺功能在英国生物银行
Nicola P Bondonno1,2,3, Pratik Pokharel1,2, Benjamin H Parmenter1,3
1Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Australia. n.bondonno@ecu.edu.au.
适度饮用茶和咖啡 (每天大约2杯) 与更好的肺功能和较低的慢性阻塞性肺病 (COPD) 和成人喘风险有关. 由于混因素,高摄入量可能不会提供好处.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 以前的研究表明,茶/咖啡消费与呼吸系统健康之间存在非线性关系.
- 摄入量较低可能与风险降低有关,而摄入量较高可能带来未知的风险.
- 慢性阻塞性肺病 (COPD) 和成人发作的喘是严重的公共卫生问题.
研究的目的:
- 研究茶和咖啡摄入量与患COPD的风险之间的关联.
- 检查茶和咖啡摄入量与成人喘风险之间的联系.
- 评估不同消费水平对肺功能和炎症的影响.
主要方法:
- 利用了来自366,869名英国生物库参与者的数据.
- 通过食物频率问卷和24小时饮食回忆来评估茶和咖啡的摄入量.
- 采用多变量调整的线性回归来进行横截面肺功能/炎症分析以及可克斯比例危险模型来预测COPD/喘发病率.
主要成果:
- 低摄入量 (每天0.5-2杯) 的茶和咖啡与改善肺功能,减少炎症以及较低的COPD和喘风险相比,与不摄入茶和咖啡有关.
- 具体来说,茶的摄入量显示了HR 0.87 (0.81,0.93) 和咖啡的摄入量HR 0.86 (0.82,0.92) 对于COPD.
- 咖啡摄入量显示喘的HR为0.90 (0.85,0.95). 高茶摄入量显示,在从不吸烟者中,COPD风险增加,可能是由于混或反向因果关系.
结论:
- 适度饮用茶和咖啡 (每天大约2杯) 可以成为健康饮食的一部分.
- 大量的茶和咖啡摄入量可能不会为呼吸系统健康带来额外的益处.
- 吸烟和反向因果关系的潜在混可能会影响在高摄入水平下观察到的关联.
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