童年时期的白衣高血压和左心室几何状况
Serap Ata1, Duygu Övünç Hacıhamdioğlu2, Deniz Cihan3
1Department of Pediatrics, Ümraniye Training and Research Hospital, Istanbul, Türkiye.
Blood pressure
|December 18, 2025
概括
白袍高血压 (WCH) 与正常体重儿童的心脏形状异常有关,表明中等心血管风险. 这凸显了在这个人群中监测WCH的必要性.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管健康 心血管健康
- 高血压研究 高血压研究
背景情况:
- 白袍高血压 (White-coat hypertension,简称WCH) 是一种在临床环境中血压升高但在其他情况下正常的疾病.
- 儿童中WCH与心脏结构变化,特别是左心室几何学之间的关系尚未得到充分证实.
- 肥胖是心血管疾病的已知危险因素,但WCH对肥胖儿童和正常体重儿童心脏几何学的影响需要调查.
研究的目的:
- 调查儿童白衣高血压 (WCH) 与左心室几何异常之间的关联.
- 为了比较正常体重和肥胖的高血压,WCH和正常血压的儿童中异常左心室几何的患病率.
- 为了确定WCH是否代表儿科人群中心血管风险的中间状态.
主要方法:
- 一个回顾性,单中心研究,涉及儿童分为肥胖和正常体重组.
- 参与者包括患有高血压,WCH和正常压力对照的儿童.
- 用心声和门诊血压监测来评估心脏结构和血压模式.
主要成果:
- 在体重正常的儿童中,随着高血压的严重程度,左心室几何异常的患病率显著增加,从对照组的1%增加到WCH的9.4%,高血压的25.8%.
- 在肥胖儿童中,异常的左心室几何在所有组中普遍存在 (19.3%至45.8%),但并没有显示血压现型严重程度的逐渐增加.
- 与对照组相比,正常体重的患有WCH的儿童中,异常左心室几何形状的患病率明显高于对照组.
结论:
- 白外套高血压 (WCH) 与正常体重儿童的左心室几何异常有关,这表明它可能是中等心血管风险标志物.
- 这些发现强调了在正常体重儿童中识别和监测WCH对于预防性心脏病学的重要性.
- 需要在更大的纵向队列中进行进一步的研究,以阐明WCH和肥胖之间对心血管结果的相互作用.
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