异性丸激素使用和急性中部严重的视网膜病变在一个跨性别患者
Benjamin J Fowler1,2, Kathleen R Schildroth1
1Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Retinal cases & brief reports
|December 18, 2025
概括
外源性使用的高水平可能与跨性别男性的中央血清性胆色素变异症 (CSCR) 有关. 在此案例报告中,光动力学疗法和降低丸激素剂量有效治疗了CSCR.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
背景情况:
- 中央血清性胆红蛋白病变 (CSCR) 是一种影响视力的疾病,通常发生在中年男性身上.
- 外源激素使用,特别是在CSCR发育中的作用尚未得到充分证实.
研究的目的:
- 为了报道一个发展了CSCR的跨性别男性患者.
- 调查外源性的使用与跨性别个体中CSCR之间的潜在关联.
主要方法:
- 一份病例报告,详细介绍了一位患有CSCR的跨性别男性患者的呈现和管理.
- 分析患者病史,水平, fundus成像和治疗结果.
主要成果:
- 一名63岁的跨性别男性长期接受外源性丸激素治疗,接受了CSCR.
- 他们发现水平升高 (962-1,179 ng/dL).
- 在半流动光动疗法 (PDT) 和降低的剂量后,视网膜下液体消失,在15个月后没有复发.
结论:
- 外源性的使用和血清水平升高可能与跨性别患者的CSCR有关.
- 光动力疗法和降低丸激素剂量似乎是这种人群中CSCR的有效治疗方法.
- 眼科医生应该考虑丸激素在CSCR病理生理学中的作用以及补充剂的潜在副作用.
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