柬埔寨狂犬病暴露后预防不完成的驱动因素,2019年至2022年
Herman Banza Kongolo1,2,3,4, Yiksing Peng5, Malen Chan1
1Epidemiology and Public Health Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.
PLoS neglected tropical diseases
|December 18, 2025
概括
柬埔寨的狂犬病暴露后预防接种疫苗 (PEPV) 不完成率很低,但有所不同,旅行时间是关键障碍. 需要针对男性和年轻人制定有针对性的战略,以实现"30岁前零"目标.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 这是一个很棒的节目,这是一个很棒的节目.
- 零乘以30的时间为零.
- 该倡议旨在到2030年消除由狗传播的狂犬病引起的人类死亡,依靠及时的暴露后预防接种疫苗 (PEPV).
- 柬埔寨面临着高狂犬病负担,需要有效的PEPV策略.
研究的目的:
- 在实施简化1周方案后,分析柬埔寨狂犬病PEPV未完成的趋势.
- 确定导致PEPV未完成的关键因素.
主要方法:
- 从2019年到2022年,对239,874名患者进行了回顾性分析,这些患者参加了柬埔寨巴斯图尔研究所 (IPC) 的狂犬病预防中心 (RPC).
- 多变量回归分析以确定与PEPV未完成相关的因素.
主要成果:
- 整体PEPV未完成率为6.4%.
- 增加到RPC的旅行时间与较低的出席率和完成率密切相关.
- 男人和年轻人 (15-29岁) 的未完成率较高;在COVID-19限制期间完成率下降.
结论:
- 虽然整体PEPV不完成率很低,但存在显著的时间和空间变化.
- 分散PEPV交付对于克服旅行时间障碍和减少不平等至关重要.
- 建议针对高风险群体提供有针对性的沟通和灵活的服务,以支持高风险群体的发展.
- 零乘以30的时间为零.
- 一个目标. 目标.
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