在跨导管三干预中三右心室陷:三研究
Tatyana Storozhenko1, Giulio Russo2, Marc Vanderheyden3
1Hartcentrum Aalst, AZORG, Aalst, Belgium; Department of Prevention and Treatment of Emergency Conditions, L.T. Malaya Therapy National Institute NAMSU, Kharkiv, Ukraine.
JACC. Clinical electrophysiology
|December 18, 2025
概括
三管横导管边缘到边缘修复 (T-TEER) 对现有右心室 (RV) 节奏线索的患者是安全的. 该研究发现,在T-TEER后没有显著的RV功能障碍或需要干预,这表明其中期安全性.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 三管横导管边缘到边缘修复 (T-TEER) 有效治疗严重的三管吐.
- 以前存在的右心室 (RV) 节奏导线可能在T-TEER后出现功能障碍.
研究的目的:
- 评估T-TEER后RV节奏线索的2年安全性和功能结果.
- 评估T-TEER对RV性能和潜在并发症的影响.
主要方法:
- 来自Tri-LEAD多中心国际注册表 (2015-2023) 的146名患者的回顾性分析.
- 主要结局:在T-TEER后2年,RV功能障碍 (通过功能变化,脱离或骨折来定义).
- 二次结局包括由于功能障碍或心脏并发症而需要干预.
主要成果:
- 在557天的中位数随访期间,观察到VR探测,阻抗和值的最小变化.
- 没有发生RV骨折,脱或心脏穿孔的病例.
- T-TEER与复合安全终点的风险增加无关 (aSHR: 1.39; P = 0.41).
结论:
- 在T-TEER中,没有任何短期或中期对转静脉RV性能的不利影响.
- 对于需要T-TEER的患者来说,该程序是一种安全的选择,具有内置的RV节奏.
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