光光谱色谱映射用于草药的非破坏性认证
Jiawei Feng1, Guirong Bu2, Xigui Song2
1College of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Journal of pharmaceutical and biomedical analysis
|December 18, 2025
概括
这项研究引入了一种新的光光谱法,用于验证草药的真实性. 该技术使用光谱和色彩分析准确区分正品和假冒产品.
科学领域:
- 分析化学 分析化学
- 药理学是指药理学,它是指药理学.
- 频谱学是一种光谱学.
背景情况:
- 确保草药的真实性对于患者的安全和治疗疗效至关重要.
- 当前的识别方法往往缺乏所需的准确性,实用性或定量能力.
- 强大的技术的有限可用性阻碍了草药质量的可靠验证.
研究的目的:
- 开发和验证一种基于量化,非破坏性的光方法来验证草药的真实性.
- 为了区分正宗的 Ziziphi Spinosae 精液 (ZSS),Aurantii Fructus (AF) 和 Carthami Flos (CF) 与它们常见的假冒品.
- 为实践草药验证建立光谱和色谱特征分析.
主要方法:
- 在365nm紫外线激发下利用高光谱成像来捕获ZSS,AF,CF及其假冒产品的光谱.
- 提取了关键光谱特征,以识别真伪样本之间的区分特征.
- 应用快速公式拟合 (FFF) 和神经网络拟合 (NNF) 来将频谱特征映射到色度特性.
主要成果:
- 使用FFF和NFF来绘制光谱和色度特征的高相关系数 (0.985-0.999) 获得.
- 确定了最佳光谱范围 (400-780 nm和470-780 nm) 以进行基于颜色的歧视,指导未来的便携式设备过器选择.
- 经过高精度的像素级认证证明,由定义的色彩可视化区域支持.
结论:
- 开发的基于光的高光谱成像技术为草药的真实性提供了定量,准确和非破坏性的方法.
- 这种方法促进了简单可靠的验证,为低成本的便携式真实检测系统铺平了道路.
- 这些发现支持光谱和色度分析的整合,以加强草药行业的质量控制.
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