提高HPV疫苗覆盖率的学校接种疫苗干预措施的过程评估:一种混合方法研究,嵌入法国PrevHPV集群随机对照试验中
Aurélie Bocquier1, Simon Cadoret2, Estelle Fall3
1Université de Lorraine, Inserm, INSPIIRE, F-54000 Nancy, France.
Vaccine
|December 18, 2025
概括
在学校进行的人类乳头瘤病毒 (HPV) 接种疫苗的干预显示出高满意度,但面临实施挑战,包括同意管理. 提供了建议,以改善学校环境中的HPV疫苗覆盖率.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在全球范围内,人类乳头瘤病毒疫苗 (HPV VC) 覆盖率仍然不够理想.
- 预防HPV计划通过集群随机对照试验 (cRCT) 评估了一项"学校接种疫苗"干预措施.
- 过程评估分析了干预的实施,影响机制和上下文因素.
研究的目的:
- 评估"在学校接种疫苗"对HPV的干预措施的实施和有效性.
- 确定影响干预成功的促进者和障碍.
- 为改善学校HPV疫苗接种计划提供建议.
主要方法:
- 在PrevHPV cRCT (2021年4月至2022年4月) 中嵌入的混合方法研究.
- 干预涉及移动疫苗接种小组 (MVT),在学校场地免费提供HPV疫苗接种.
- 数据收集包括活动报告,问卷 (青少年,学校工作人员) 和重点小组 (学校工作人员,MVT).
主要成果:
- 39%的随机分类学校退学;17%的青少年返回同意表,其中89%开始接种疫苗.
- MVT和学校工作人员对于实施至关重要;参与者的满意度很高.
- 促进者包括员工的可用性和动机;障碍物包括同意表格和健康记录.
结论:
- "学校接种疫苗"的干预有潜力,但需要解决实施挑战,特别是同意管理.
- 为法国学校的HPV疫苗接种活动和潜在的立法改进制定了建议.
- 该研究提供了扩大学校接种疫苗计划的见解,以加强HPV VC.
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