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Updated: Jan 8, 2026

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity
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拉巴胺通过通过mTORC1-C/EBPβ-OSM轴重新编程Cxcl9+巨细胞,从而在自身免疫性心肌炎中保持心脏功能

Yan Zhuang1, Yongcui Yan1, Zheng Wen1

  • 1Division of Cardiology and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Redox biology
|December 18, 2025
PubMed
概括

拉巴胺通过mTORC1-C/EBPβ-OSM通路重新编程炎症性巨细胞来治疗自身免疫性心肌炎. 针对OSM提供了一个有前途的治疗策略,用于心肌炎和心力衰竭.

关键词:
Cxcl9(+) 大细胞炎症性心肌病变性是什么肌肉性心脏炎是一种心肌炎.拉帕米辛是一种在mTOROR中使用mTOR.

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