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评估药物发现和开发中的DDI风险:方法,挑战和趋势

Hong-Can Ren1, Chunyong He2, Hong Wan3

  • 1Department of DMPK, Genescience Pharmaceuticals Co., Ltd. Research and Development, Shanghai, China.

Expert opinion on drug metabolism & toxicology
|December 18, 2025
PubMed
概括

药物相互作用 (DDI) 既带来风险又带来机遇. 使用人工智能和PBPK建模等先进工具的战略管理对于药物开发至关重要,特别是在瘤学中.

关键词:
药物药物相互作用 (DDI)基于生理学的药理动力学 (PBPK)人工智能 (AI) 是一种人工智能.药物开发是药物的发展.发现药物的发现.它们是内源生物标志物.酶抑制/诱导 酶抑制/诱导药物动力学 (PK) 是指

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