职业作为慢性病进展的危险因素:回顾性队列研究
Daisuke Takada1,2, Susumu Kunisawa1, Akira Kikuno3
1Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto City, Kyoto, Japan.
Journal of occupational health
|December 18, 2025
概括
职业类型影响慢性病 (CKD) 的进展. 某些行业显示,估计质过率 (eGFR) 降低的风险较低,这表明社会经济因素会影响脏健康.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 职业健康 职业健康 职业健康
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 的病因通常不清楚.
- 社会经济地位越来越被认为是CKD进展的一个因素.
研究的目的:
- 调查18个职业分类与CKD进展风险之间的关联.
- 用大规模的健康检查和保险索赔数据库分析CKD进展情况.
主要方法:
- 利用了日本健康保险协会的数据 (2012年4月至2016年3月).
- 定义CKD进展为估计膜过率 (eGFR) 降低>30%.
- 采用了考克斯的比例风险模型,调整了多个健康和人口学变量.
主要成果:
- 在平均2.8年的随访期间分析了239,506名员工.
- 确定了1,736个 (0.7%) 个体具有显著的eGFR下降.
- 与"制造业"相比,在"信息和通信"",运输"",住宿"",个人服务"和"医疗保健/福利"部门发现eGFR下降风险较低.
结论:
- 职业类型是CKD进展风险的重要决定因素.
- 特定行业可能提供预防功能衰退的保护因素.
- 需要进一步的研究来阐明机制和因果关系.
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