与神经相关的骨髓炎
Milo Patrick Delaney1, Shiran Ajith Paranavitane2, Larissa Mulka3
1Neurology, King's College Hospital NHS Foundation Trust, London, England, UK milo.delaney@nhs.net.
Practical neurology
|December 18, 2025
概括
神经是一种罕见的骨髓炎原因,可以呈现为超急性带综合征. 及时诊断和用抗生素和类固醇治疗导致一名患有这种罕见神经复杂症的年轻人持续康复.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 脊髓医学 脊髓医学
背景情况:
- 梅毒是一种复杂的传染病,具有多样化的神经表现.
- 骨髓炎是梅毒的一种罕见但严重的神经复杂症.
- 超急性带综合征需要快速诊断和干预.
研究的目的:
- 报告一个罕见的神经病病例,呈现为骨髓炎.
- 突出诊断挑战和梅毒性脑膜炎的临床特征.
- 强调在急性骨髓病中考虑神经病的重要性.
主要方法:
- 一个29岁的男性患有突然发作的的病例报告.
- 临床检查显示,松的残肢,具有特定的感官水平.
- 脊柱MRI显示纵向扩展性骨髓炎,具有特征性成像发现.
- 通过血清和脑脊液中的阳性梅毒血清学来确认诊断.
主要成果:
- 患者出现了突然的双边腿部软弱,背部疼痛和尿液保留.
- 脊柱MRI揭示了纵向扩展的骨髓炎与"沟"和"翻转"的迹象.
- 梅毒血清学在血清和脑脊液中均呈阳性.
- 观察到对皮质类固醇和抗微生物药物治疗的剧烈和持续反应.
结论:
- 在超急性脑膜炎的差异诊断中,应考虑神经.
- 早期诊断和治疗对于梅毒性脑膜炎的良好结果至关重要.
- 典型的MRI发现可以帮助诊断这种罕见的疾病.
更多相关视频
09:46Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
Published on: September 21, 2021
5.1K
07:30A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
10.0K
相关概念视频
Nervous Tissue: Myelin
5.2K
The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
5.2K
Myasthenia Gravis: Overview and Treatment
2.7K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
2.7K
