在儿科中,疹病毒感染的异常呈现
Ahmed Aaid Osman1, Fuad Fajer Fuad Kara'een2, Wimal Nettikumara2
1Paediatrics, East Sussex Healthcare NHS Trust, Saint Leonards-on-Sea, UK ahmed.osman34@nhs.net.
BMJ case reports
|December 18, 2025
概括
疹病毒 (Varicella-Zoster Virus,简称VZV) 可以导致神经问题,如头痛和内压力增加,即使没有典型的水或带状疹症状. 静脉注射的阿西克洛维尔有效地治疗了这些与VZV相关的神经并发症.
科学领域:
- 病毒学 病毒学
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 疹病毒建立了终身潜伏状态,并且可以在压力下重新激活.
- 疹病毒 (Varicella-Zoster Virus,简称VZV) 或人类疹病毒3型,导致水和带状疹.
- VZV的重新激活可能会出现非典型的神经症状.
研究的目的:
- 报告一种主要表现为神经症状的VZV病例.
- 为了突出VZV脑膜炎/脑炎的诊断挑战.
- 为了证明阿西克洛维尔在治疗VZV神经疾病中的有效性.
主要方法:
- 案例报告分析.情况报告分析.
- 临床检查和神经学评估.
- 脑脊液 (CSF) 的分析.
- 用静脉注射阿西克洛维尔治疗.
主要成果:
- 患者表现为头痛,内压升高,脑液多细胞症和乳头,缺乏发烧或皮疹.
- 鉴定出VZV是病原体.
- 静脉注射阿西克洛维尔导致显著的临床改善和CSF发现的正常化.
结论:
- 在出现神经症状的情况下,即使没有皮疹,也应该考虑VZV.
- 早期诊断和阿西克洛维尔治疗对于管理VZV引起的神经并发症至关重要.
- 这一案例强调了VZV重新激活的多样化临床表现.
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