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Updated: Jan 8, 2026

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从血小板和中性粒细胞中合作释放的线粒体DNA驱动系统性硬化症中的干扰素特征

Stavros Giaglis1,2, André N Tiaden1,2, Simone Häner-Massimi1,2

  • 1Laboratory for Experimental Rheumatology, Department of Biomedicine, University of Basel, Basel, Switzerland.

Arthritis & rheumatology (Hoboken, N.J.)
|December 18, 2025
PubMed
概括

系统性硬化症 (SSc) 患者的循环线粒体DNA (mtDNA) 水平显著更高,这种DNA被氧化并促进自身释放,导致炎症和组织损伤.

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