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Updated: Jan 8, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
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由NSUNs驱动的失调:针对性癌症治疗的下一个前沿?

Yingqi Zhao1,2, Yuying Zhang1,2, Haonan Zhou3

  • 1Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.

Cell death & disease
|December 18, 2025
PubMed
概括

RNA甲基化,特别是5-甲基细胞因 (m5C),在癌症中至关重要. NSUN 蛋白质,m5C 作者,调节瘤进展,并为精确瘤学提供新的治疗点.

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Targeted Cancer Therapies

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Adaptive Mechanisms in Cancer Cells

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Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
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