患者报告结果在健康技术评估中的作用:全球实践和未来影响
Nenad Medic1, James Ryan2, Calvin N Ho3
1Late Cardiovascular, Renal & Metabolism R&D, AstraZeneca, Cambridge, UK.
将患者报告的结果 (PRO) 数据纳入卫生技术评估 (HTA) 是有限的. 解决数据准确性和技术专业知识等障碍对于更好的付款人决策至关重要.
科学领域:
- 卫生经济学 卫生经济学
- 患者为中心的研究成果研究成果
背景情况:
- 患者报告的结果 (PRO) 数据捕捉了患者对疾病和治疗的看法.
- 目前在医疗技术评估 (HTA) 和退款决定中使用PRO数据是有限的.
研究的目的:
- 探索将PRO纳入付款人决策中的考虑因素.
- 确定在HTA中采用PRO数据的障碍.
主要方法:
- 审查了关于PRO使用的支付人指导文件 (至2024年) 和科学文献 (2015-2024年).
- 与15名国际专家对HTA中的PRO使用进行了一对一的采访.
主要成果:
- PRO指导通常侧重于仪器有效性,可靠性,偏见,缺少的数据和经济建模,国际上存在很大的差异.
- 专家采访强调,PRO采用取决于既定的终点和付款人框架.
- 关键障碍包括缺乏专业知识,对仪器有效性和数据准确性的担忧.
结论:
- 克服PRO数据使用障碍需要所有利益相关者的协作努力.
- 促进PRO注册对于加强付款人决策过程至关重要.
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