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相关概念视频

Introduction to Cognitive Psychology01:20

Introduction to Cognitive Psychology

2.1K
Cognitive psychology is the field of psychology dedicated to examining how people think. It attempts to explain how and why we think the way we do by studying the interactions among human thinking, emotion, creativity, language, and problem-solving, as well as other cognitive processes. Cognitive psychology studies how information is processed and manipulated in remembering, thinking, and knowing.
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

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A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
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Information Processing Approach01:30

Information Processing Approach

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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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Cognitivism01:17

Cognitivism

2.6K
Cognitive psychology emerged as a significant field in the mid-20th century. It focused on understanding humans' internal mental processes. This approach emphasizes how people perceive, remember, think, and solve problems—elements critical to human cognition.
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
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Updated: Jan 8, 2026

Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
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Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage

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基于可解释的人工智能的认知衰老时钟

Mikhail I Krivonosov1,2, Tatiana A Khabarova3, Elena V Kondakova4,3

  • 1Institute of Biogerontology, Lobachevsky State University, Nizhny Novgorod, Russia. krivonosov@itmm.unn.ru.

npj aging
|December 18, 2025
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种新的认知衰老时钟,使用五种测试来评估衰老. 时钟准确地预测认知年龄,识别痴呆症患者的加速衰老.

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A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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科学领域:

  • 神经科学是一个神经科学.
  • 老年学是一门学科.
  • 计算生物学 计算生物学

背景情况:

  • 生物钟估计了有关衰老的生物体生理状态.
  • 加速衰老与增加的死亡率和发病率风险有关.
  • 现有的时钟主要关注生理衰老,需要认知衰老评估.

研究的目的:

  • 使用机器学习模型开发和验证一种认知衰老时钟.
  • 识别有助于认知年龄估计的关键认知领域.
  • 研究认知障碍患者的认知衰老加速.

主要方法:

  • 采用了五项认知测试的电池:感觉运动算术,感觉运动镜子字母,1-背,营地测量和Stroop测试.
  • 一个LightGBM机器学习模型被开发来预测认知年龄.
  • 用SHAP (夏普利添加式扩展) 分析来解释模型.

主要成果:

  • 认知衰老时钟实现了7.6年的平均绝对误差 (MAE).
  • SHAP分析揭示了Stroop和野战测试对认知年龄的占主导地位.
  • 痴呆症患者的认知年龄显著加速;在中度认知障碍中观察到趋势.
  • 蒙特利尔认知评估 (MoCA) 的得分显示,与认知年龄偏差有负面关联.

结论:

  • 开发的认知衰老时钟为认知衰老提供了可靠的衡量标准.
  • 斯特鲁普和营地测量测试是认知年龄的关键指标.
  • 认知衰老加速是痴呆症的一个重要特征,突出显示了时钟的临床相关性.