在结直肠癌患者中,循环结直肠切除术闭合后细菌转位的危险因素
Toshiyuki Adachi1, Yusuke Inoue2, Satomi Okada2
1Department of Surgery, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. t-adachi@nagasaki-u.ac.jp.
International journal of colorectal disease
|December 18, 2025
概括
术后辅助化疗可能会增加结直肠癌患者在结直肠静脉关闭后细菌转移 (BT) 的风险. 在患有BT的患者中观察到更高的C-反应蛋白水平.
科学领域:
- 结肠直肠外科手术是什么意思
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 结肠直肠癌手术后的乳房静脉关闭很少会导致败血症休克.
- 在这些情况下,细菌转移 (BT) 是疑似造成败血症休克的原因.
- 识别BT的风险因素对于患者管理至关重要.
研究的目的:
- 在接受结直肠癌手术的患者中,研究结直肠瘤关闭后与细菌转位 (BT) 相关的风险因素.
主要方法:
- 在结肠直肠癌手术后,对91名接受结肠直肠关闭术的患者进行了回顾性分析.
- 患者被分为两组:患有BT (没有明确原因的高于38°C的发烧) 和没有BT的患者.
- 分析了患者背景,手术和术后因素的数据.
主要成果:
- 在91名患者中,有12名患者发生了细菌转位 (BT).
- 与非BT组相比,在手术后的第3天和第7天,在BT组中观察到显著更高的C-反应蛋白水平.
- 在BT组中,更高比例的患者接受了术后辅助化疗 (83.3%对43.0%).
结论:
- 术后辅助化疗是结肠直肠癌患者的结肠直肠切除术关闭后细菌转移 (BT) 的重要危险因素.
- 较高的C-反应蛋白水平可能表明BT的风险增加.
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