在人类婴儿的运动发育过程中神经运动模块的功能对称化
Jiayin Lin1, Sophia C W Ha2, Janet H Zhang-Lea3
1School of Biomedical Sciences and Gerald Choa Neuroscience Institute, The Chinese University of Hong Kong, Hong Kong, China.
Communications biology
|December 18, 2025
概括
婴儿肌肉协同作用和肢体生物力学共同发展,导致对称的行走模式,以保持稳定. 这种终身发展优化了步态控制和效率.
科学领域:
- 发育神经科学的发展神经科学.
- 生物力学 生物力学
- 发动机控制器 发动机控制器
背景情况:
- 新生儿神经运动控制模块,或肌肉协同作用,在人类运动发育过程中成熟,使其能够独立行走.
- 早期肌肉协同作用,发育的神经肌肉骨系统和感觉运动可塑性之间调节这一过程的相互作用尚未得到充分理解.
研究的目的:
- 研究人类运动发育过程中肌肉协同作用,动力协同作用和下肢生物力学特性同时发生的变化.
- 分析这些变化跨支持和独立行走阶段和整个生命周期.
主要方法:
- 在4个行走阶段的11名婴儿中进行了纵向双边多肌肉记录和动态跟踪.
- 个性化神经肌肉骨模型.
- 整合成人和老年人的数据,进行全生命周期分析.
主要成果:
- 最初双边不对称的肌肉协同作用和肢体的生物力学特性共同演变.
- 这种共同进化的结果是对称的动力协同作用,可能会稳定步伐.
- 神经运动模块的功能对称反映了步行稳定性和效率的共同发展.
结论:
- 步态的发展涉及肌肉协同作用,动力学功能和肢体生物机械性质的共同进化.
- 神经运动模块的对称性对于实现整个寿命的步行稳定性和控制效率至关重要.
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