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相关概念视频

Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

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Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
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Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
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相关实验视频

Updated: Jan 8, 2026

Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope
14:09

Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope

Published on: April 7, 2014

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边缘阶段 (EdgePhase):一种便携式边缘计算显微镜,用于在护理中心进行定量阶段成像.

Wei Wang, Yaxi Li, Huachuan Huang

    Optics express
    |December 19, 2025
    PubMed
    概括
    此摘要是机器生成的。

    一个新的便携式显微镜,EdgePhase,集成成像,计算和显示,用于点的护理测试. 这种紧的设备可以在没有外部设备的情况下进行野外显微镜,从而提升了移动诊断能力.

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    Phase Contrast and Differential Interference Contrast DIC Microscopy
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    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture
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    相关实验视频

    Last Updated: Jan 8, 2026

    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope
    14:09

    Quantitative Optical Microscopy: Measurement of Cellular Biophysical Features with a Standard Optical Microscope

    Published on: April 7, 2014

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    Phase Contrast and Differential Interference Contrast DIC Microscopy
    06:49

    Phase Contrast and Differential Interference Contrast DIC Microscopy

    Published on: August 6, 2008

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    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture
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    Lens-free Video Microscopy for the Dynamic and Quantitative Analysis of Adherent Cell Culture

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    科学领域:

    • 显微镜的使用方法
    • 生物医学工程 生物医学工程
    • 计算成像技术的成像

    背景情况:

    • 传统的显微镜很庞大,需要外部平台来处理数据,限制了医疗点测试 (PoCT) 应用.
    • 现有的便携式显微镜往往缺乏集成的计算和显示,阻碍了现场部署.
    • 需要独立的,便携式显微镜解决方案,用于远程和现场诊断.

    研究的目的:

    • 开发一个便携式,全合一的计算显微镜,用于现场应用.
    • 将成像,边缘计算,存储和可视化集成到一个紧的设备中.
    • 为了克服当前便携式显微镜对外部平台依赖的局限性.

    主要方法:

    • 开发了一个便携式边缘计算显微镜EdgePhase (18.80 × 20.34 × 19.57厘米3).
    • 集成了一个紧的定量相位成像系统与边缘计算平台,监视器和可充电电源.
    • 利用并行计算用于双焦图像采集,相位检索,数据存储和1024 × 1024 像素图像的> 10 fps 的可视化.

    主要成果:

    • 实现了>10fps的率,并集成了平行计算用于图像采集,相位检索和显示.
    • 验证了相位重建的准确性,并证明了动态和现场相位成像能力.
    • 通过自闭式便携式系统成功成像活细胞和血液涂抹.

    结论:

    • EdgePhase为边缘计算显微镜提供了一个实用,便携式的解决方案.
    • 综合设计使得基于现场诊断和PoCT的独立操作成为可能.
    • 这一发展提升了移动显微镜在各种环境中实时分析的潜力.